Ctgf sirna
WebSep 4, 2024 · Connective tissue growth factor (CTGF), also known as CCN2, is a member of the CCN (CCN1-6) ... Kras siRNA, IL6 siRNA, CTGF siRNA, STAT-3 siRNA, and control siRNA (Thermo Fisher Scientific) were transfected into the cells using Lipofectamine RNAiMAX (Thermo Fisher Scientific) according to the reverse transfection … WebPushing through the pipeline OLX101, which targets the connective tissue growth factor (CTGF) gene, is OliX’s most advanced program, and is in clinical development as an …
Ctgf sirna
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Web靶向大鼠ctgf的shrna表达载体的构建和作用分析. 内容摘要:作者:郎明健,曾秋棠,郭敏,杨汉东,闵新文 作者:郎明健,曾秋棠,郭敏,杨汉东,闵新文 目的:构建并筛选靶向大鼠结缔组织生长因子(ctgf)的shrna表达载体.方法:根据大鼠ctgfmrna序列设计并构建4个靶向 … WebJul 31, 2015 · Connective tissue growth factor (CTGF) is a critical fibrogenic mediator of TGF-β1. Mammalian sirtuin 1 (Sirt1) is reported to attenuate renal fibrosis by inhibiting …
WebApr 12, 2024 · The primer sequences were as follows: TAZ 5′-CACCGTGTCCAATCACCAGTC-3′ (forward); 5′-TCCAACGCATCAACTTCAGGT-3′ … WebCTGF siRNA transfection led to significant decreases in mRNA and protein levels for CTGF in both a dose- and time-dependent manner. mRNA levels for types I and III procollagen, …
WebFeb 16, 2024 · To investigate the roles of YAP in regulation of CTGF expression, YAP siRNA or YAP function inhibitor (Verteporfin, 2 μM, s1786, Selleck Chemicals, Houston, USA) was incubated before hypoxia to ... WebsiRNA products generally consist of pools of three to five target-specific 19-25 nt siRNAs designed to knockdown gene expression; for independent verification of CTGF gene …
WebJan 8, 2015 · These results suggest that TGF-β 1-siRNA delivery with NPs is a promising therapeutic approach for the inhibition of PF. Liposome-based NPs have been reported …
WebBackground: Connective tissue growth factor (CTGF) is a highly profibrogenic molecule implicated in hepatic fibrogenesis. Small interfering RNA (siRNA) is an effective tool to … hide a bed sizeWebJan 1, 2024 · Connective tissue growth factor (CTGF) produced by tumor cells is critical for the production of IL-6 family cytokines, which can activate STAT3 in hepatoma cells, stromal cells such as hepatic stellate cells (HSCs), macrophages, T cells, and endothelial0020cells. ... HepG2 cells were transfected with CTGF siRNA or control … howell nj senior center activitiesWebDownload scientific diagram CTGF regulates collagen in HEK293-MAS cells treated with MAS agonist (AR234960). MAS expressing HEK293 cells were transiently transfected with control siRNA and CTGF ... howell nj taxi serviceWebHere, we examine the anti-fibrotic activity of RNAi therapy utilizing siRNA against CTGF with a new drug delivery system (DDS), ‘DegradaBALL’, which is based on porous … howell nj senior center newsletterWeb目的:构建pET32a- TrxA- His- CTGF- CT原核表达载体,实现重组CTGF- CT的可溶性表达及分离纯化,以用于制备CTGF- CT抗体。方法:基因合成CTGF- CT序列,利用NcoI和XhoI限制性内切酶双酶切后插入pET32a载体,构建pET32a- TrxA- His- CTGF- CT重组质粒,阳性质粒转化E.colistrain BL21(DE3 ... hide a beds near meWebDec 9, 2024 · Transfection of Small Interfering RNA. The mRNA sequences of rat CTGF (NM_022266) were acquired from NCBI GenBank. Small interfering RNA (siRNA) against rat CTGF was designed and synthesized by GenePharma Biological Company (Shanghai, China). howell nj senior centerWeb47 CTGF Silencer Select Pre-designed, Validated, and Custom siRNA in Standard, HPLC, and In-vivo Ready Purities. Sign in. Don't have an account ? ... connective tissue growth factor: Ccn2;Fisp12;Hcs24;fisp-12: NM_010217.2: This page works best with JavaScript enabled! Assay ID 10580 View Assay on Map Gene. CTGF. hide a bed slip cover